Open AccessJudging a Fish by Its Ability to Climb a Tree? A Call for Novel Endpoints in the Appraisal of Ablative Local Treatments of Oligometastatic Cancer
Author(s) -
Loi Mauro,
Alifano Marco,
Scorsetti Marta,
Nuyttens Joost J.,
Livi Lorenzo
Publication year - 2021
Publication title -
the oncologist
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.176
H-Index - 164
eISSN - 1549-490X
pISSN - 1083-7159
DOI - 10.1002/onco.13747
Subject(s) - medicine , ablative case , clinical endpoint , clinical trial , fish <actinopterygii> , oncology , intensive care medicine , radiation therapy , fishery , biology
This commentary addresses the need for novel endpoints in clinical research to assess the added value of local treatment of metastases in oligometastatic patients and in patients experiencing limited metastatic progression during systemic therapy (oligoprogressive). Novel metrics are proposed for future implementation in clinical trials.