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Collision gas effects in the collision‐induced decomposition of protonated and cationized molecules of carbohydrate antibiotics
Author(s) -
Florencio M. Helena,
Despeyroux Dominique,
Jennings Keith R
Publication year - 1994
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210290907
Subject(s) - protonation , fragmentation (computing) , argon , mass spectrum , chemistry , molecule , ion , mass spectrometry , helium , collision induced dissociation , yield (engineering) , decomposition , analytical chemistry (journal) , tandem mass spectrometry , materials science , organic chemistry , chromatography , computer science , metallurgy , operating system
The collision‐induced decomposition (CID) mass spectra of the protonated and cationized molecules of a number of carbohydrate antibiotics of RMM ranging from 700 to 1500 were studied by means of a four‐sector mass spectrometer with a floated collision cell. Helium and argon were used as collision gases. This work illustrates that cationized rather than protonated carbohydrate antibiotics give an increased yield of high‐mass ions of diagnostic value. Further, when helium is replaced by argon as collision gas, differences in the CID spectra of MH + ions become apparent only for molecules of RMM > 1400 whereas for [M + Na] + ions differences are observed for molecules of RMM as low as 1000. These results have been attributed to the deposition of more internal energy in the precursor ion when argon is used, resulting in increased fragmentation.