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Mass spectra of n ‐butylboronate ester derivatives of the major metabolite of prostaglandin F
Author(s) -
Ferretti Aldo,
Flanagan Vincent P.,
Roman John M.
Publication year - 1994
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210290706
Subject(s) - fragmentation (computing) , chemistry , metabolite , mass spectrum , substituent , ion , deuterium , mass spectrometry , dissociation (chemistry) , prostaglandin , collision induced dissociation , spectral line , stereochemistry , derivative (finance) , medicinal chemistry , chromatography , organic chemistry , biochemistry , physics , tandem mass spectrometry , biology , quantum mechanics , financial economics , economics , ecology , astronomy
The EI mass spectra of six n ‐butylboronate ester derivatives of the major metabolite of prostaglandins F 1α and F 2α (PGF‐M) are presented and discussed. Proposed ion assignments and fragmentation pathways are based on substituent shifts, on data from a deuterium‐labeled methoxime derivative and on the analysis of collision‐induced dissociation spectra of selected ions. Fragment ions suitable for identification and quantification of PGF‐M in a biological matrix and diagnostically valuable ions for structure recognition are proposed.