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Analysis of amino acid mixtures by plasma desorption mass spectrometry
Author(s) -
Hoppilliard Yannik,
Mauriac Christine
Publication year - 1993
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210280908
Subject(s) - desorption , chemistry , mass spectrometry , mass spectrum , ion , amino acid , ionization , chromatography , analytical chemistry (journal) , field desorption , chemical ionization , adsorption , organic chemistry , biochemistry
Plasma desorption mass spectrometry (PDMS) was investigated as a means of analysing mixtures of three, four and five amino acids in both positive‐ and negative‐ion modes. Fifteen mixtures were tested; each mixture contained equimolar amounts of selected amino acids. The PD mass spectra exhibited MH + and [M – H] − molecular ions for all the aminoacids with different desorption–ionization yields. The spectra were more easily interpreted in the negative‐ than the positive‐ion mode. The desorption order of the amino acids was progressively established by comparing the molecular ion desorption–ionization yields for each mixture. This desorption order was well correlated in both the positive‐ and negation‐ion modes with the acid–base thermodynamic data for the amino acids in the gas phase. This observation gives some insight into the desorption–ionization mechanisms under PDMS conditions.