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Electron impact mass spectrometry of some 6‐substituted tetrazolo[1,5‐ c ]pyrimidin‐5(6 H )‐ones
Author(s) -
Płaziak Adam S.,
Celewicz Lech,
Ciszewski Krzysztof,
Golankiewicz Krzysztof
Publication year - 1993
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210280528
Subject(s) - fragmentation (computing) , chemistry , electron ionization , azide , tetrazole , tautomer , mass spectrum , metastability , ion , mass spectrometry , nucleoside , polyatomic ion , computational chemistry , medicinal chemistry , crystallography , stereochemistry , organic chemistry , ionization , chromatography , computer science , operating system
Abstract The electron impact mass spectra of 6‐methyltetrazolo[1,5‐ c ]pyrimidin‐5(6 H )‐one, its 7‐ and 8‐methyl derivatives, three 8‐halo derivatives and two related nucleosides are reported. On the basis of the high‐resolution data and detected metastable ions, the fragmentation routes of their molecular ions are proposed. Coexistence of the tautomeric forms of the title compounds of cyclic (tetrazole) or linear (azide) structure can be suggested owing to the fragmentation pathways identified for the bases. Decomposition of the related nucleosides lies in the breaking of nucleoside bonds to produce the appropriate base and sugar fragments.