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Ortho effect in the mass spectrometric behaviour of N (pyrimidin‐4‐yl)aminobenzoic acids and their methyl esters
Author(s) -
Plaziak Adam S.,
Spychala Jaroslaw,
Wójtowicz Hanna,
Langer Jerzy J.,
ThielPawlicka Halina,
Golankiewicz Krzysztof
Publication year - 1992
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210271124
Subject(s) - substituent , chemistry , moiety , aminobenzoic acid , deuterium , p aminobenzoic acid , fragmentation (computing) , mass spectrometry , electron ionization , medicinal chemistry , organic chemistry , stereochemistry , chromatography , ion , biochemistry , physics , quantum mechanics , computer science , ionization , operating system
Ortho‐. meta ‐ and para ‐isomers of N ‐(pyrimidin‐4‐yl)aminobenzoic acid and their methyl esters were investigated by electron impact mass Spectrometry. Their fragmentation was found to be strongly dependent on the position of the substituent in the aminobenzoic moiety. Two different kinds of ortho effect were studied and confirmed with the aid of deuterium‐labelled derivatives.