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Fourier transform ion cyclotron resonance study of ion‐molecule reactions of [M – OCH 3 ] + ions of methyl 2,3,4,6‐tetra‐ O ‐methyl‐d‐hexopyranosides with ammonia
Author(s) -
Kovacik Vladimir,
Hirsch Janos,
Thölmann Detlef,
Grützmacher HansFriedrich
Publication year - 1991
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210261210
Subject(s) - fourier transform ion cyclotron resonance , chemistry , ion cyclotron resonance , ion , adduct , molecule , mass spectrometry , ammonia , tetra , photochemistry , medicinal chemistry , organic chemistry , cyclotron , chromatography
Abstract Glycosidic oxocarbenium ions A 1 + were formed by isobutane chemical ionization from methyl 2,3,4,6‐tetra‐ O ‐methyl‐β‐ D ‐mannopyranoside, methyl 2,3,4,6‐tetra‐ 0 ‐methyl‐β‐ D ‐galactopyranoside and methyl 2,3,4,6‐tetra‐ O ‐methyl‐β‐ D ‐glucopyranoside (the ring ‐ O‐being converted into O ), and then‐ reaction with ammonia was studied by Fourier transform ion cyclotron resonance Spectrometry. Very slow formation (reaction efficiency 0.6‐1.4%) of the adduct ion [A 1 + NH 3 ] 4 was observed as the main process for carefully thermalized ions A 1 + . Interestingly, the efficiency of the adduct ion formation depends on the sterochemistry of ions A 1 + .