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Matrix‐assisted laser desorption of neutral organic molecules
Author(s) -
Kinsel Gary R.,
Lindner Josef,
Grotemeyer Jürgen
Publication year - 1991
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210261204
Subject(s) - desorption , molecule , ionization , matrix (chemical analysis) , wavelength , laser , explosive material , fragmentation (computing) , materials science , analytical chemistry (journal) , matrix isolation , chemistry , optics , ion , organic chemistry , adsorption , optoelectronics , composite material , physics , computer science , operating system
Results of initial investigations of matrix‐assisted laser desorption (LD) of neutral molecules are presented. The investigations were performed using gramicidine D as the test molecule, since both the wavelength‐dependent LD beharioor and the ionization and fragmentation behaviour of the pure material had been studied previously. Comparisons between previously reported results for the pure compound and the matrix mixtures used in these studies are made. The results show that, whereas no signal could be observed from the pure sample material at non‐resonant desorbing wavelengths, addition of a strongly absorbing matrix to the sample initiated LD of abundant intact neutral sample molecules. The results are discussed in the light of previous studies of the LD mechanism and support an explosive, mechanically driven model for the LD process.