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Unique thermospray mass spectrometry of 1,4‐benzoquinone and analogs in ammonium acetate solutions
Author(s) -
Gctek T. A.,
Vestal M. L.,
Vestal C. H.,
Korfmacher W. A.,
Miller D. W.,
Freeman J. P.
Publication year - 1991
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210260806
Subject(s) - thermospray , chemistry , ammonium acetate , mass spectrometry , amine gas treating , conjugate , ion , ammonium , chromatography , benzoquinone , electrochemistry , aqueous solution , methanol , mass spectrum , inorganic chemistry , high performance liquid chromatography , tandem mass spectrometry , organic chemistry , selected reaction monitoring , electrode , mathematical analysis , mathematics
Abstract In general, ions corresponding to [M + H] + and/or [M + NH 4 ] + are observed in thermospray mass spectrometry (TSMS) when using ammonium acetate in the liquid carrier. For several quinones investigated, unique thermospray mass spectra were detected with a mass spectral peak corresponding to an [M + 16] + ion being observed in aqueous ammonium acetate solutions. Investigation of l,4‐benzoquinone (BQU) and structurally analogous quinones indicated that amine conjugate formation with BQU and similar quinones was the origin of the unique [M + 16] + ion in TSMS. When methanol was added to the liquid carrier, ions corresponding to methoxy conjugation were detected. High‐performance liquid chromatography followed by TSMS or electrochemical detection gave evidence that this amine and methoxy conjugate formation was occurring in the thermospray source area.