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Fast atom bombardment and secondary ion mass spectra of thiamine hydrochloride
Author(s) -
Brown Stephen M.,
Busch Kenneth L.,
Burinsky David J.
Publication year - 1989
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210240502
Subject(s) - ion , mass spectrum , chemistry , fast atom bombardment , analytical chemistry (journal) , protonation , spectral line , mass spectrometry , chromatography , physics , organic chemistry , astronomy
The ratio of the fragment ions at m / z 122 and m / z 123 in the positive ion fast atom bombardment or secondary ion mass spectra of thiamine hydrochloride varies with sample preparation and experimental conditions. For all mass spectra that contained significant abundances of matrix (S) ions [S + H] + , the fragment at m / z 123 is the more abundant of the two ions. If [S + H] + ions are not observed in the mass spectrum under the conditions selected, the ion at m / z 122 is more abundant. This correlation suggests that hydrogen transfer to the fragment ion occurs in the gas phase, with the composition of the ion‐solvent cluster ions in the selvedge region being the key factor. The ratio of the fragment ions at m / z 123 and m / z 122 is thus an indicator of the extent of protonation in the selvedge, the region immediately above the solvent surface created by primary particle bombardment.