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Mass spectra of dihydroxy stereoisomers of 3‐methoxy‐1,3,5(10)‐estratrienes
Author(s) -
Schade Wolfgang,
Schubert Gerd,
Schönecker Bruno
Publication year - 1988
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210230406
Subject(s) - mass spectrum , fragmentation (computing) , spectral line , electron ionization , chemistry , ion , diol , mass spectrometry , medicinal chemistry , analytical chemistry (journal) , stereochemistry , organic chemistry , ionization , physics , chromatography , astronomy , computer science , operating system
Electron impact mass spectral data for each of the four isomeric 16,17‐, 15,17‐ and 14,17‐diols of 3‐methoxy‐1,3,5(10)‐estratriene and the 15,17‐diols of 3‐methoxy‐14β‐1,3,5(10)‐estratriene are reported. The mass spectra of the diols show very similar fragmentation patterns except for differences in the relative abundances of particular ions. The different [M − H 2 O] + ˙/[M] + ˙ and [M − 2H 2 O] + ˙ [M] + ˙ ratios can be used for distinguishing between the four isomeric 3‐methoxy‐1,3,5(10)‐estratriene‐14,17‐diols as well as between the four isomeric 3‐methoxy‐14β‐1,3,5(10)‐estratriene‐15,17‐diols. No significant differences could be detected in the spectra of the epimeric 16,17‐and 15,17‐diols of 3‐methoxy‐1,3,5(10)‐estratriene.