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Mass spectra of some 1‐(6′‐substituted‐4′‐methyl‐2′‐quinolyl)‐3‐methylpyrazol‐5‐ols and their 4‐substituted analogues
Author(s) -
Singh Shiv P.,
Vaid Radhe K.,
Prakash Om
Publication year - 1987
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210220407
Subject(s) - moiety , intramolecular force , fragmentation (computing) , chemistry , ion , mass spectrum , pyrazole , ring (chemistry) , medicinal chemistry , stereochemistry , organic chemistry , computer science , operating system
Electron impact induced fragmentation of some 1‐(6′‐substituted‐4′‐metbyI‐2′‐quinolyI)‐3‐methylpyrazoI‐5‐ols follows a route where the pyrazole moiety is preferentially cleaved with successive losses of two moieties of 41 u. High‐resolution measurements have established that the first loss is due to the Ċ 2 HO moiety, which necessitates an intramolecular hydrogen transfer followed by ring fission. The resultant ion loses CH 3 CN in a subsequent step. The origin of many fragment ions was traced with the use of B/E linked‐scan spectra.