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Stereochemical effects in mass spectrometry. 3—Detection of chirality by chemical ionization mass spectrometry
Author(s) -
Suming Hua,
Yaozu Chen,
Longfei Jiang,
Shuman Xue
Publication year - 1986
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210210103
Subject(s) - mass spectrometry , chemistry , chemical ionization , chirality (physics) , mass spectrum , reagent , ionization , molecule , enantiomer , atmospheric pressure chemical ionization , ion , alcohol , analytical chemistry (journal) , electron ionization , chromatography , organic chemistry , chiral symmetry , physics , quantum mechanics , nambu–jona lasinio model , quark
Abstract It was found that the chemical ionization mass spectra of the enantiomers of some α‐amino acids and α‐hydroxy acids could be definitely distinguished when a chiral compound, l ‐amyl alcohol, was used as a component of the reagent gases. The relative abundances of some characteristic ions produced through ion‐molecule reactions in the gas phase were much higher in the D isomers than in the L isomers. The results were highly reproducible. This approach proved to be a convenient way for the detection of the chirality of these compounds by chemical ionization mass spectrometry.