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Chemical ionization mass spectrometric characteristics of morphine alkaloids
Author(s) -
Liu Ray H.,
Low I. A.,
Smith Frederick P.,
Piotrowski Edwin G.,
Hsu Anfei
Publication year - 1985
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210200806
Subject(s) - chemistry , protonation , reagent , adduct , chemical ionization , mass spectrometry , ion , ammonia , polyatomic ion , molecule , deuterium , mass spectrum , ionization , inorganic chemistry , organic chemistry , chromatography , physics , quantum mechanics
Abstract The ion‐molecular reaction behavior of ten morphine alkaloids with several commonly used reagent gases are studied under chemical ionization mass spectrometry conditions. These studies emphasize the correlation of the structural characteristics of the 10 alkaloids with the following four mass spectrometric parameters: (i) mass shifts of the protonated ion as a result of replacing ammonia with deuterated ammonia as the reagent gas, (ii) relative tendencies of the adduct ion and the protonated ion to lose molecules of water, (iii) relative intensity ratio of the adduct ion and the protonated ion and (iv) tendency of a compound to undergo a reduction reaction.