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Mass spectrometry of nitroazoles: 3— ortho effects: The loss of OH ˙ and H 2 O from methyl substituted nitrodiazoles
Author(s) -
Luijten W. C. M. M.,
van Thuijl J.
Publication year - 1982
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210170702
Subject(s) - deuterium , chemistry , methyl group , hydrogen , ring (chemistry) , labelling , hydrogen atom , mass spectrometry , medicinal chemistry , stereochemistry , group (periodic table) , organic chemistry , physics , atomic physics , chromatography , biochemistry
Methyl substituted nitrodiazoles which have the substituents at adjacent positions in the ring are subject to several ortho effects. Deuterium labelling of the methyl group and the mobile N‐bonded hydrogen show that the loss of OH ˙ originates from the substituents. In some cases the N‐bonded hydrogen atom participates also in the loss of OH ˙ and of H 2 O .