Electrophilic aromatic substitution under chemical ionization conditions. Methylamine and ammonia as reagent gases | Zendy

Luijten W. C. M. M. | Zendy; Onkenhout W. | Zendy; van Thuijl J. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Electrophilic aromatic substitution under chemical ionization conditions. Methylamine and ammonia as reagent gases

Author(s) -

Luijten W. C. M. M.,

Onkenhout W.,

van Thuijl J.

Publication year - 1980

Publication title -

organic mass spectrometry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.475

H-Index - 121

eISSN - 1096-9888

pISSN - 0030-493X

DOI - 10.1002/oms.1210150702

Subject(s) - chemistry , methylamine , nitrobenzene , reagent , adduct , ammonia , medicinal chemistry , electrophilic substitution , substitution reaction , inorganic chemistry , ion , chemical ionization , ionization , organic chemistry , catalysis

For compounds C 6 H 5 X (XCl, Br, I) under chemical ionization conditions, methylamine causes ipso substitution of X by [NH 2 CH 3 ] + and by [NH 2 ] + ˙. C 6 H 5 F is less reactive; it gives some [C 6 H 5 NH 2 ] + ˙. Nitrobenzene gives an adduct ion [M+CH 3 NH 3 ] + , a reduction product ion [C 6 H 5 NO 2 ] + ˙, and an ion at m / z 93, probably a substitution product [C 6 H 5 NH 2 ] + ˙, but no [C 6 H 5 NH 2 CH 3 ] + . It is also shown that the ion m / z 94, formed from nitrobenzene with ammonia as reagent gas, is a substitution product rather than a reduction product ion. Carbonyl compounds C 6 H 5 . CO. X give adduct ions and some substitution, mainly [C 6 H 5 NH 2 ] + ˙.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research