Premium
Secondary ion mass spectrometry of nucleic acid components: Pyrimidines, purines, nucleosides and nucleotides
Author(s) -
Eicke A.,
Sichtermann W.,
Benninghoven A.
Publication year - 1980
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210150605
Subject(s) - chemistry , mass spectrometry , mass spectrum , ion , purine metabolism , nucleic acid , nucleotide , molecule , ionization , polyatomic ion , ion source , analytical chemistry (journal) , organic chemistry , chromatography , biochemistry , gene , enzyme
Biologically important involatile organic compounds including nucleotides, nucleosides, purines and pyrimidines have been analysed by secondary ion mass spectrometry. For the emission of molecule‐like secondary ions small amounts of the substances were deposited as thin layers on silver foils and bombarded with 3 keV [AR] + ions. All the compounds investigated yielded intense molecular ions of the general composition [M±H] ± and [M + Ag] + , but only a few characteristic fragment ions due to simple bond cleavages. Similarities and differences as compared with spectra obtained by other mass spectrometric ionization techniques are illustrated and discussed.