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A comparison of electron impact and field ionization spectra of some 2,5‐diketopiperazines
Author(s) -
Szafranek Janusz,
Palacz Zbigniew,
Grzonka Zbigniew
Publication year - 1976
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210110903
Subject(s) - diketopiperazines , fragmentation (computing) , electron ionization , mass spectrum , chemistry , mass spectrometry , spectral line , field desorption , ionization , piperazine , stereochemistry , organic chemistry , chromatography , physics , ion , astronomy , computer science , operating system
Abstract The mass spectra of cyclo‐(Gly‐Leu), cyclo‐(Gly‐Tyr), cyclo‐(Ala‐Tyr), cyclo‐(Leu‐Tyr), cyclo‐(Val‐Phe) and cyclo‐(Leu‐Phe) are presented. The use of high resolution mass measurements and metastable analysis allows the proposal of some general fragmentation mechanisms. The dominant features in the mass spectra of 2,5‐diketopiperazines are fragments corresponding to cleavages of sidechains and the rupture of the piperazine‐2,5‐dione ring. The characteristic fragments may be used in the identification of any 2,5‐diketopiperazines by mass spectrometry.