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A study of the ortho effects and rearrangement processes in the mass spectra of 2‐arylaminothiazine and ‐thiazoline derivatives
Author(s) -
Bujtás Gy.,
Tamás J.
Publication year - 1976
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210110707
Subject(s) - chemistry , intramolecular force , mass spectrum , ion , mass spectrometry , thiazoline , labelling , decomposition , electron ionization , ring (chemistry) , rearrangement reaction , photochemistry , computational chemistry , medicinal chemistry , stereochemistry , organic chemistry , catalysis , biochemistry , chromatography , ionization
The behaviour of the title compounds under electron impact has been investigated using low and high resolution mass spectrometry and partial 15 N and D labelling. A number of ions produced by rearrangement were observed. Abundant ions are formed by intramolecular ortho substitution reactions (cyclizations), as demonstrated by energetic and kinetic considerations and by studying the decomposition pathways of these ions. The ortho substitution processes involve loss or rearrangement of an ortho group of the aromatic ring.