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Heterocyclic studies—XXIX: Mass spectra of some 1,2‐dihydro‐5‐trifluoromethyl‐pyrimido(5,4‐E) AS ‐triazines
Author(s) -
Clark Jim
Publication year - 1973
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210070212
Subject(s) - fragmentation (computing) , substituent , chemistry , mass spectrum , trifluoromethyl , deuterium , labelling , triazine , mass spectrometry , spectral line , medicinal chemistry , computational chemistry , organic chemistry , chromatography , physics , biochemistry , nuclear physics , alkyl , astronomy , computer science , operating system
Mass spectra of five 7‐substituted‐1,2‐dihydro‐5‐trifluoromethylpyrimido(5,4‐e)as‐triazine derivatives are recorded. Fragmentation pathways, elucidation of which was assisted by deuterium labelling and accurate mass measurements, are compared with those of corresponding heteroaromatic compounds. Loss of HF initiated the major breakdown pathways, unless a large 7‐substituent was present, which then fragmented preferentially.