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The mass spectra of some 2,1,3‐benzothiadiazoline and 2,1,3‐benzothiadiazine 2,2‐dioxides
Author(s) -
Bancroft K. C. C.,
Guindi L. H. Morcos,
Temple A. F.,
Millard B. J.
Publication year - 1972
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210061206
Subject(s) - benzothiadiazine , chemistry , mass spectrum , mass spectrometry , deuterium , derivative (finance) , labelling , medicinal chemistry , molecule , stereochemistry , organic chemistry , chromatography , biochemistry , physics , quantum mechanics , financial economics , economics
Although the behaviour of 1 H , 2 H ‐2,1,3‐benzothiadiazoline 2,2‐dioxide is similar to that of sulphoxides in the mass spectrometer in losing a molecule of SO 2 , the 1,3‐dimethyl derivative loses the radical SO 2 H. In addition the radical CH 3 SO 2 is lost in a one step process that must involve a methyl migration. The radical SO 2 H is also lost from 2,1,3‐benzothiadiazine 2,2‐dioxides methylated in the 3‐position and the hydrogen involved is shown to originate from this methyl group by deuterium labelling. The mass spectra of other 2,1,3‐benzothiadiazine 2,2‐dioxides are also discussed.