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Heterocyclic studies—XXIV: Mass spectra of some pteridin‐4(3H)‐ones and 3‐methoxypteridin‐4(3H)‐ones
Author(s) -
Clark Jim,
Maynard Ruth,
Smith C.
Publication year - 1971
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210050812
Subject(s) - chemistry , fragmentation (computing) , pyrazine , stereochemistry , pyrimidine , mass spectrum , ring (chemistry) , ion , organic chemistry , biology , ecology
Mass spectra of pteridin‐4(3H)‐one and all its mono‐, di‐ and tri‐C‐methyl derivatives are recorded. Spectra of 3‐methoxypteridin‐4(3H)‐one and four of its mono‐ and dimethyl derivatives are also recorded. Pteridin‐4(3H)‐one fragments mainly by loss of CO and HCN in either order. Methyl substitution in the pyrazine ring leads to that ring fragmenting in preference to the oxygen bearing pyrimidine ring. Elucidation of fragmentation pathways was facilitated by changes in peak positions with changing methyl substitution patterns. 3‐Methoxypteridin‐4(3H)‐ones fragment mainly through initial loss of CH 2 O, but the ions so produced break down differently from isomeric molecular ions of pteridin‐4(3H)‐ones. Several fragmentation pathways are discussed.