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The loss of CO and HCN in the fragmentation of isatin and the methyl isatins
Author(s) -
Butcher M.
Publication year - 1971
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210050616
Subject(s) - isatin , fragmentation (computing) , chemistry , molecule , methyl group , medicinal chemistry , organic chemistry , group (periodic table) , biology , ecology
3‐ 13 C‐Isatin has been shown to eliminate the 2‐carbonyl group as the initial fragment, followed predominantly by loss of HCN. In 4‐, 5‐and 6‐methyl‐isatin the loss of the second carbonyl group competes evenly with HCN loss, whilst the 7‐methyl isomer fragments almost exclusively by successive loss of two molecules of CO from the molecular ion.