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Mass spectrometry in structural and stereochemical problems—CCIV. Spectra of hydantoins II. Electron impact induced fragmentation of some substituted hydantoins
Author(s) -
Corral Reneé A.,
Orazi Orfeo O.,
Duffield A. M.,
Djerassi Carl
Publication year - 1971
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210050507
Subject(s) - hydantoin , chemistry , fragmentation (computing) , alkyl , mass spectrum , electron ionization , mass spectrometry , medicinal chemistry , ring (chemistry) , ion , stereochemistry , organic chemistry , chromatography , computer science , ionization , operating system
The mass spectral decomposition modes of hydantoin and derivatives containing alkyl and phenyl substituents have been investigated using isotopic labeling techniques. The loss of carbon monoxide from the molecular ions of these compounds was shown to preferentially involve the C‐4 carbonyl group. Other fragmentation processes characteristic of the hydantoin ring system and the effect on this of alkyl and phenyl substitution are described.