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The fragmentation of organic molecules under electron‐impact—III: The mass spectra of some substituted thioureas
Author(s) -
Baldwin M. A.,
Kirkien Alicja M.,
Loudon A. G.,
Maccoll Allan
Publication year - 1970
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210040109
Subject(s) - alkyl , fragmentation (computing) , chemistry , mass spectrum , aryl , electron ionization , thiourea , molecule , medicinal chemistry , organic chemistry , photochemistry , ionization , ion , computer science , operating system
The mass spectra of some alkyl thioureas, alkyl–aryl and aryl thioureas are presented and discussed. The main primary fragmentation pathways are cleavage next to the central carbon atom, with the charge residing on either fragment, and the loss of sulphydryl or substituted sulphydryl radicals. The differences in behaviour of the methyl ureas and thioureas are discussed on the basis of a preferred charge location on sulphur in the thioureas but on nitrogen in the ureas. Also, where appropriate, the spectra of all the alkyl compounds are compared with those of the alkyl guanidines. The effect of chain length of alkyl groups and of charge location on the fragmentation pattern is discussed using the spectra of the ethyl and butyl thioureas and the ethyl ureas. The sensitivity of alkyl thioureas to pyrolysis is noted and the sensitivity of phenyl substituted thioureas to pyrolysis confirmed.