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On the loss of ammonia from phenylalkyl amines
Author(s) -
Lightner D. A.,
Sunderman F. W.,
Hurtado L.,
Thommen E.
Publication year - 1970
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210031012
Subject(s) - dimethylamine , amine gas treating , methylamine , chemistry , fragmentation (computing) , ammonia , primary (astronomy) , deuterium , ion , medicinal chemistry , liquid ammonia , hydrogen , organic chemistry , physics , quantum mechanics , astronomy , computer science , operating system
The molecular ion‐minus‐ammonia [M – NHJ] fragmentation of (3‐phenylpropyl) primary amines is a major contributor to the total ion current. This fragmentation occurs to a lesser extent in the lower and higher homologs, (2‐phenethy1)‐ and (4‐phenylbuty1)amine. The loss of methylamine and dimethylamine from N‐methyl‐(3‐phenylpropyl)amine and N,N‐dimethyl‐(3‐phenylpropy1)amine respectively is essentially absent. Deuterium labeling has shown that C‐3 is the primary source of hydrogen abstracted in the [M NHJ] fragmentation of (3‐pheny1propyl)amine.