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The electron‐impact induced loss of water from meconine and related derivatives
Author(s) -
King Bonnie M.,
Evans D. A.,
Biemann K.
Publication year - 1970
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210030809
Subject(s) - fragmentation (computing) , mass spectrum , electron ionization , chemistry , deuterium , polyatomic ion , ion , photochemistry , computational chemistry , medicinal chemistry , stereochemistry , organic chemistry , ionization , atomic physics , physics , computer science , operating system
The mass spectrum of meconine (I), a constituent of raw opium, exhibits several anomalous features (e.g. pronounced loss of H 2 O from the molecular ion) which are not readily explicable in terms of simple fragmentation processes. The study of the low resolution mass spectrum of meconine and its derivatives in conjunction with deuterium labeling experiments has indicated a highly specific fragmentation mechanism in which both hydrogen atoms eliminated as H 2 O originate from the methoxy function ortho to the lactone carbonyl group in meconine.