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The mass spectra of N‐adamantoylpeptides
Author(s) -
Lengyel István,
Salomon Ramon A.,
Biemann Klaus
Publication year - 1970
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210030609
Subject(s) - tripeptide , dipeptide , chemistry , valine , alanine , mass spectrum , phenylalanine , amino acid , peptide , leucine , isoleucine , mass spectrometry , histidine , methionine , glycine , stereochemistry , chromatography , threonine , serine , organic chemistry , biochemistry , enzyme
The N‐adamantoyl derivatives of the esters of twenty‐one di‐peptides and eight tri‐peptides containing the amino acids glycine, alanine, valine, leucine, isoleucine, proline, phenylalanine, glutamic acid, lysine, histidine, serine, threonine, methionine, S‐benzylcysteine and tyrosine were prepared and their mass spectra determined. The spectra of all compounds were suitable for amino acid sequence determination. Mixtures containing N‐adamantoyl dipeptide and tripeptide methyl esters were separated by thin‐layer chromatography and the components identified by high resolution mass spectrometry. The mass spectrometric features of N‐adamantoyl peptide esters are discussed and compared with those of other N‐acyl peptide derivatives.