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The mass spectrometry of volatile derivatives—III: N‐aryl trifluoracetamides
Author(s) -
Saxby M. J.
Publication year - 1969
Publication title -
organic mass spectrometry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.475
H-Index - 121
eISSN - 1096-9888
pISSN - 0030-493X
DOI - 10.1002/oms.1210020810
Subject(s) - substituent , fragmentation (computing) , chemistry , polyatomic ion , ion , mass spectrometry , aryl , molecule , ring (chemistry) , medicinal chemistry , photochemistry , organic chemistry , chromatography , alkyl , computer science , operating system
The effects of substituents on the fragmentation of N‐aryl trifluoracetamides has been investigated. The base peak in all ring‐monosubstituted derivatives is the molecular ion. Other important ions arise by loss of CF 3 and COCF 3 from the molecular ion, and the latter daughter ion fragments further, by loss of the aromatic substituent and by expulsion of small neutral molecules. The effects of substituents on the intensity of these ions is discussed. 1‐Phenylethyl trifluoracetamide exhibits a base peak which is the molecular ion, wheras the corresponding 2‐phenyl derivative has a molecular ion of very low intensity.