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A model for the complex of the ( R )‐MTPA ester of trans ‐4‐ tert ‐butylcyclohexanol with Eu(fod) 39 based on lanthanide induced shifts
Author(s) -
Vanhoeck L.,
Merckx E. M.,
Bossaerts J.,
Lepoivre J. A.,
Alderweireldt F. C.
Publication year - 1983
Publication title -
organic magnetic resonance
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.483
H-Index - 72
eISSN - 1097-458X
pISSN - 0030-4921
DOI - 10.1002/omr.1270210316
Subject(s) - moiety , lanthanide , conformational isomerism , chemistry , stereochemistry , medicinal chemistry , organic chemistry , molecule , ion
It is shown that the complexation of Eu(fod) 3 with the MTPA ester of trans ‐4‐ tert ‐butylcyclohexanol is very similar to that of ketones with Eu(fod) 3 . It is found to be more likely that the MTPA moiety can exist as two rotamers, suggesting that earlier models for correlating LIS and absolute configuration are inadequate.
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