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Describing the Weight‐Reduced State: Physiology, Behavior, and Interventions
Author(s) -
Aronne Louis J.,
Hall Kevin D.,
M. Jakicic John,
Leibel Rudolph L.,
Lowe Michael R.,
Rosenbaum Michael,
Klein Samuel
Publication year - 2021
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1002/oby.23086
Subject(s) - weight loss , gerontology , obesity , medicine , psychological intervention , thermogenesis , physiology , psychology , endocrinology , psychiatry
Although many persons with obesity can lose weight by lifestyle (diet and physical activity) therapy, successful long‐term weight loss is difficult to achieve, and most people who lose weight regain their lost weight over time. The neurohormonal, physiological, and behavioral factors that promote weight recidivism are unclear and complex. The National Institute of Diabetes and Digestive and Kidney Diseases convened a workshop in June 2019, titled “The Physiology of the Weight‐Reduced State,” to explore the mechanisms and integrative physiology of adaptations in appetite, energy expenditure, and thermogenesis that occur in the weight‐reduced state and that may oppose weight‐loss maintenance. The proceedings from the first session of this workshop are presented here. Drs. Michael Rosenbaum, Kevin Hall, and Rudolph Leibel discussed the physiological factors that contribute to weight regain; Dr. Michael Lowe discussed the biobehavioral issues involved in weight‐loss maintenance; Dr. John Jakicic discussed the influence of physical activity on long‐term weight‐loss maintenance; and Dr. Louis Aronne discussed the ability of drug therapy to maintain weight loss.