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Overweight and Obesity are Risk Factors of Severe Illness in Patients with COVID‐19
Author(s) -
Wang Jian,
Zhu Li,
Liu Longgen,
Zhao Xiangan,
Zhang Zhaoping,
Xue Leyang,
Yan Xuebing,
Huang Songping,
Li Yang,
Cheng Juan,
Zhang Biao,
Xu Tianmin,
Li Chunyang,
Ji Fang,
Ming Fang,
Zhao Yun,
Shao Huaping,
Sang Dawen,
Zhao Haiyan,
Guan Xinying,
Chen Xiaobing,
Chen Yuxin,
Issa Rahma,
Wei Jie,
Huang Rui,
Zhu Chuanwu,
Wu Chao
Publication year - 2020
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1002/oby.22979
Subject(s) - overweight , medicine , obesity , covid-19 , diabetes mellitus , pneumonia , risk factor , disease , endocrinology , infectious disease (medical specialty)
Objective This study aimed to observe the clinical characteristics of patients with coronavirus disease 2019 (COVID‐19) with overweight and obesity. Methods Consecutive patients with COVID‐19 from 10 hospitals of Jiangsu province, China, were enrolled. Results A total of 297 patients with COVID‐19 were included, and 39.39% and 13.47% of patients had overweight and obesity, respectively. The proportions of bilateral pneumonia (92.50% vs. 73.57%, P = 0.033) and type 2 diabetes (17.50% vs. 3.57%, P = 0.006) were higher in patients with obesity than lean patients. The proportions of severe illness in patients with overweight (12.82% vs. 2.86%, P = 0.006) and obesity (25.00% vs. 2.86%, P < 0.001) were significantly higher than lean patients. More patients with obesity developed respiratory failure (20.00% vs. 2.86%, P < 0.001) and acute respiratory distress syndrome (5.00% vs. 0%, P = 0.024) than lean patients. The median days of hospitalization were longer in patients with obesity than lean patients (17.00 days vs. 14.00 days, P = 0.029). Overweight (OR, 4.222; 95% CI: 1.322‐13.476; P = 0.015) and obesity (OR, 9.216; 95% CI: 2.581‐32.903; P = 0.001) were independent risk factors of severe illness. Obesity (HR, 6.607; 95% CI: 1.955‐22.329; P = 0.002) was an independent risk factor of respiratory failure. Conclusions Overweight and obesity were independent risk factors of severe illness in COVID‐19 patients. More attention should be paid to these patients.