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Associations of Pregnancy After Bariatric Surgery with Long‐Term Weight Trajectories and Birth Weight: LABS‐2 Study
Author(s) -
Harrod Curtis S.,
Elman Miriam R.,
Vesco Kimberly K.,
Wolfe Bruce M.,
Mitchell James E.,
Pories Walter J.,
Pomp Alfons,
BooneHein Janne,
Purnell Jonathan Q.
Publication year - 2020
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1002/oby.22944
Subject(s) - medicine , pregnancy , weight loss , gastric bypass , body mass index , offspring , birth weight , obstetrics , weight change , weight gain , longitudinal study , obesity , surgery , body weight , genetics , pathology , biology
Objective This study aimed to examine whether pregnancy following bariatric surgery affects long‐term maternal weight change and offspring birth weight. Methods Using data from the Longitudinal Assessment of Bariatric Surgery (LABS)‐2 study, linear regression was used to evaluate percent change in total body weight over a 5‐year follow‐up period among reproductive‐aged women who underwent Roux‐en‐Y gastric bypass or laparoscopic adjustable gastric banding as well as evaluate the association of bariatric procedure type and offspring birth weight. Results Of 727 women with preoperative age of 36.1 (6.3) years (mean [SD]) and BMI of 46.9 (7.0) kg/m 2 , 80 (11%) reported at least one pregnancy. After adjusting for covariates, percent change in total body weight was not significantly different between women who became pregnant and those who did not during a 5‐year follow‐up period (β = 2.02; 95% CI: −1.03 to 5.07; P = 0.19). Additionally, mean birth weight was not significantly different between mothers who underwent Roux‐en‐Y gastric bypass versus laparoscopic adjustable gastric banding ( P = 0.99). Conclusions Postoperative pregnancy did not diminish long‐term weight loss in women in the LABS‐2 study. The finding of comparable weight loss is relevant for providers counseling women of reproductive age on weight‐loss expectations and family planning following bariatric surgery.