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Association Between Lifestyle and Hypertriglyceridemic Waist Phenotype in the PREDIMED‐Plus Study
Author(s) -
FernándezGarcía José Carlos,
MuñozGarach Araceli,
MartínezGonzález Miguel Ángel,
SalasSalvado Jordi,
Corella Dolores,
Hernáez Álvaro,
Romaguera Dora,
Vioque Jesús,
AlonsoGómez Ángel M.,
Wärnberg Julia,
Martínez J. Alfredo,
SerraMajem Luís,
Estruch Ramón,
Lapetra José,
Pintó Xavier,
Tur Josep A.,
GarciaRios Antonio,
García Molina Laura,
Gaforio José Juan,
MatíaMartín Pilar,
Daimiel Lidia,
Martín Sánchez Vicente,
Vidal Josep,
Prieto Lucia,
Ros Emilio,
Goñi Nuria,
Babio Nancy,
OrtegaAzorin Carolina,
Castañer Olga,
Konieczna Jadwiga,
Notario Barandiaran Leyre,
VaqueroLuna Jessica,
BenaventeMarín Juan Carlos,
Zulet M. Angeles,
SanchezVillegas Almudena,
Sacanella Emilio,
Gómez Huelgas Ricardo,
MiróMoriano Leticia,
GimenezGracia Mariano,
Julibert Alicia,
Razquin Cristina,
Basora Josep,
Portolés Olga,
Goday Albert,
GalmésPanadés Aina M.,
LópezGarcía Carmen M.,
MorenoRodriguez Anai,
Toledo Estefanía,
DíazLópez Andrés,
Fitó Montserrat,
Tinahones Francisco J.,
BernalLópez M. Rosa
Publication year - 2020
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1002/oby.22728
Subject(s) - medicine , abdominal obesity , waist , metabolic syndrome , obesity , diabetes mellitus , type 2 diabetes , body mass index , gerontology , endocrinology
Objective The hypertriglyceridemic waist (HTGW) phenotype is characterized by abdominal obesity and high levels of triglycerides. In a cross‐sectional assessment of PREDIMED‐Plus trial participants at baseline, HTGW phenotype prevalence was evaluated, associated risk factors were analyzed, and the lifestyle of individuals with metabolic syndrome and HTGW was examined. Methods A total of 6,874 individuals aged 55 to 75 with BMI ≥ 27 and < 40 kg/m 2 were included and classified by presence (HTGW + ) or absence (HTGW − ) of HTGW (waist circumference: men ≥ 102 cm, women ≥ 88 cm; fasting plasma triglycerides ≥ 150 mg/dL). Analytical parameters and lifestyle (energy intake and expenditure) were analyzed. Results A total of 38.2% of the sample met HTGW + criteria. HTGW + individuals tended to be younger, have a greater degree of obesity, be sedentary, and be tobacco users. They had higher peripheral glucose, total cholesterol, and low‐density lipoprotein cholesterol levels; had lower high‐density lipoprotein cholesterol levels; and had increased prevalence of type 2 diabetes mellitus. Mediterranean diet (MedDiet) adherence and physical activity were greater in HTGW − patients. Age, BMI, tobacco use, total energy expenditure, hypertension, type 2 diabetes mellitus, and MedDiet adherence were associated with HTGW + . Conclusions HTGW is a highly prevalent phenotype in this population associated with younger age, higher BMI, tobacco use, and decreased MedDiet adherence. HTGW − individuals were more physically active with greater total physical activity, and fewer had hypertension.