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Effectiveness of a Community‐Based Weight Management Program for Patients Taking Antidepressants and/or Antipsychotics
Author(s) -
Wharton Sean,
Kuk Jennifer L.,
Petrova Lana,
Rye Peter I.,
Taylor Valerie H.,
Christensen Rebecca A.G.
Publication year - 2019
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1002/oby.22567
Subject(s) - medicine , weight gain , weight loss , psychiatry , weight management , body weight , depression (economics) , intervention (counseling) , antipsychotic , schizophrenia (object oriented programming) , obesity , economics , macroeconomics
Objective This study aimed to compare weight loss (WL) outcomes for patients taking antidepressants and/or antipsychotics with those not taking psychiatric medication. Methods A total of 17,519 adults enrolled in a lifestyle WL intervention at the Wharton Medical Clinics in Ontario, Canada, were analyzed. Sex‐stratified multivariable linear regression analysis was used to examine the association of taking antidepressants, antipsychotics, both, or neither with WL when adjusting for age, initial weight, and treatment time. Results Twenty‐three percent of patients were taking at least one psychiatric medication. Patients lost a significant amount of weight ( P < 0.0001) regardless of psychiatric medication use. Women taking psychiatric medications lost a similar amount of weight as women who were not ( P > 0.05). Conversely, men taking antidepressants lost only slightly less weight than men taking both classes or neither class of psychiatric medication (3.2 ± 0.3 kg vs. 5.6 ± 0.9 kg and 4.3 ± 0.1 kg; P < 0.05). However, taking psychiatric medications that cause weight gain was associated with similar significant decreases in weight as taking medications that are weight neutral or associated with WL for both sexes ( P > 0.05). Conclusions Results of this study suggest that those who participate in a weight management program can lose significant amounts of weight regardless of psychiatric medication use.