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Associations of Body Composition with Blood Pressure and Hypertension
Author(s) -
Ye Sunyue,
Zhu Chaonan,
Wei Chen,
Yang Min,
Zheng Weifang,
Gan Da,
Zhu Shankuan
Publication year - 2018
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1002/oby.22291
Subject(s) - confounding , medicine , blood pressure , prehypertension , lean body mass , body mass index , logistic regression , body fat percentage , odds ratio , classification of obesity , cardiology , endocrinology , body weight
Objective The present study investigated the associations of body composition, including skeletal muscle and fat mass, with blood pressure (BP) and hypertension. Methods Data from 3,130 participants aged 18 to 80 years were analyzed. Body composition and total skeletal muscle (TSM) were measured or calculated based on dual‐energy x‐ray absorptiometry. Multivariate linear and logistic regression models were used to analyze the associations of TSM, body fat percentage, android to gynoid fat ratio, and leg and arm lean body mass (LBM) with BP and hypertension. The Wald test was used to estimate the differences in the coefficients. Results TSM indices, body fat percentage, and android to gynoid fat ratio were significantly associated with higher odds ratio for prehypertension and hypertension, except for TSM/weight, after controlling for potential confounders. The standardized beta coefficients of arm LBM indices for systolic and diastolic BP were higher than relevant indices of leg LBM. Conclusions Different indices of TSM, especially in arm LBM, were all positively associated with elevated BP, prehypertension, and hypertension in Chinese adults, after considering potential confounding factors, including body fat and fat distribution. Future longitudinal studies are warranted to confirm our findings.