Premium
Association of Obesity Subtypes in the Longitudinal Assessment of Bariatric Surgery Study and 3‐Year Postoperative Weight Change
Author(s) -
Field Alison E.,
Inge Thomas H.,
Belle Steven H.,
Johnson Geoffrey S.,
Wahed Abdus S.,
Pories Walter J.,
Spaniolas Konstantinos,
Mitchell James E.,
Pomp Alfons,
Dakin Gregory F.,
Wolfe Bruce,
Courcoulas Anita P.
Publication year - 2018
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1002/oby.22287
Subject(s) - obesity , medicine , longitudinal study , weight change , weight loss , body mass index , surgery , pathology
Objective The study objective was to empirically identify subgroups of patients with obesity and investigate their association with postoperative weight change. Methods A longitudinal analysis of 2,458 adults in the Longitudinal Assessment of Bariatric Surgery (LABS) study was used. Baseline data were used to identify subgroups. The outcome was 3‐year weight change after bariatric surgery. Results We identified four classes (subtypes) of obesity, which could be characterized as diabetes with low rates of high‐density lipoprotein (Class 1), disordered eating (Class 2), mixed (Class 3), and extreme obesity with early onset (Class 4). Approximately 98% of participants in Class 1 had diabetes compared with < 40% in the other classes. There were high rates of binge eating in Class 2, and more than 92% of those in this class reported eating when not hungry. Class 4 was characterized by a higher BMI at baseline. Adults in Class 4 lost an average of 25.0% (males) and 30.3% (females) of their baseline weight over 3 years. In contrast with participants in Class 1, those in Classes 2 and 3 had significantly larger 3‐year weight losses than their peers in Class 4. Conclusions Obesity is a heterogeneous disease. Bariatric surgery may be most beneficial for adults with disordered eating.