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Phase II Feasibility Study of a Weight Loss Intervention in Female Breast and Colorectal Cancer Survivors (SWOG S1008)
Author(s) -
Greenlee Heather,
Lew Danika L.,
Hershman Dawn L.,
Newman Vicky A.,
Hansen Lisa,
Hartman Sheri J.,
Korner Judith,
Shi Zaixing,
Sardo Molmenti Christine L.,
Sayegh Antoine,
Fehrenbacher Lou,
Lo Shelly,
Klemp Jennifer,
Rinn Kristine,
Robertson John M.,
Unger Joseph,
Gralow Julie,
Albain Kathy,
Krouse Robert,
Fabian Carol
Publication year - 2018
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1002/oby.22269
Subject(s) - medicine , weight loss , breast cancer , colorectal cancer , physical therapy , weight management , obesity , telephone counseling , cancer , randomized controlled trial , gerontology
Objective This study aimed to test the feasibility of a 12‐month weight loss intervention using telephone‐based counseling plus community‐situated physical activity (PA) in female breast cancer (BC) and colorectal cancer (CRC) survivors. Methods This multisite cooperative group study enrolled sedentary, female, postmenopausal BC and CRC survivors with BMI ≥ 25 kg/m 2 to receive 12‐month fitness center memberships and telephone counseling encouraging 150 min/wk of PA and a 500‐kcal/ddecrease in energy intake. Feasibility criteria included accrual, adherence, and retention. Target weight loss was ≥ 5%. Results Among 25 BC survivors, median baseline BMI was 37.2 (range: 27.7‐54.6), accrual occurred in 10 months, 60% and 28% met diet and exercise goals, 80% provided 12‐month measures, and average weight loss was 7.6% (95% CI: −3.9%, 19.2%). Among 23 CRC survivors, median BMI was 31.8 (range: 26.4‐48.7), accrual occurred in 24 months, 61% and 17% met diet and exercise goals, 87% provided measures, and average weight loss was 2.5% (95% CI: −8.2%, 13.3%). Conclusions It is feasible to recruit and retain BC survivors in a cooperative group diet and PA weight loss trial. BC survivors achieved clinically meaningful weight loss but did not meet a priori adherence goals. In CRC survivors, recruitment was more difficult, and the intervention was less effective.