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Sedentary Time and MRI‐Derived Measures of Adiposity in Active Versus Inactive Individuals
Author(s) -
Henson Joseph,
Edwardson Charlotte L.,
Morgan Bruno,
Horsfield Mark A.,
Khunti Kamlesh,
Davies Melanie J.,
Yates Thomas
Publication year - 2018
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1002/oby.22034
Subject(s) - medicine , visceral fat , fat accumulation , subcutaneous fat , sedentary behavior , population , physical activity , intra abdominal fat , diabetes mellitus , abdominal fat , sedentary lifestyle , obesity , endocrinology , physical therapy , adipose tissue , insulin resistance , environmental health
Objective The aim of this study was to examine cross‐sectional associations between objectively measured sedentary time and magnetic resonance imaging (MRI)‐assessed adiposity in a population at high risk for type 2 diabetes (T2DM) and to determine whether associations are modified by the recommended levels of moderate‐to‐vigorous physical activity (MVPA). Methods Sedentary time and MVPA were measured objectively by using accelerometers. Linear regression models examined the association of sedentary time with liver, visceral, subcutaneous, and total abdominal fat (quantified by using MRI). Interaction terms determined whether results were consistent across activity categories (active [> 150 min/wk of MVPA] vs. inactive [< 150 min/wk of MVPA]). Results One hundred and twenty‐four participants (age = 64.0 ± 7.1 years; male = 65.3%; BMI = 31.8 ± 5.6 kg/m 2 ) were included. Following adjustment, each 60 minutes of sedentary time was associated with 1.74 L higher total abdominal fat, 0.62 L higher visceral fat, 1.14 L higher subcutaneous fat, and 1.86% higher liver fat. When results were stratified by MVPA (active vs. inactive), sedentary time was associated with greater liver, visceral, and total abdominal fat in the inactive group only. Conclusions These findings suggest that sedentary time is associated with higher levels of inter‐ and intraorgan fat, but associations with liver, visceral, and total abdominal fat were stronger in those who do not reach the current exercise recommendations for health.