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Randomized trial reveals that physical activity and energy expenditure are associated with weight and body composition after RYGB
Author(s) -
Carnero Elvis Alvarez,
Dubis Gabriel S.,
Hames Kazanna C.,
Jakicic John M.,
Houmard Joseph A.,
Coen Paul M.,
Goodpaster Bret H.
Publication year - 2017
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1002/oby.21864
Subject(s) - medicine , weight loss , quartile , adipose tissue , composition (language) , randomized controlled trial , energy expenditure , endocrinology , weight change , physical activity , skeletal muscle , weight gain , obesity , body weight , zoology , physical therapy , biology , confidence interval , linguistics , philosophy
Objective This study investigated the associations of both physical activity time (PA) and energy expenditure (EE) with weight and fat mass (FM) loss in patients following Roux‐en‐Y gastric bypass (RYGB) surgery. Methods Ninety‐six nondiabetic patients were included in this analysis. Post‐RYGB patients were randomized in one of two treatments: A 6‐month exercise training program (RYBG+EX) or lifestyle educational classes (RYGB). Body composition was assessed by dual‐energy X‐ray absorptiometry and computed tomography. Components of PA and EE were quantified by a multisensory device. Dose‐response relationships of both PA and EE with weight loss and body composition were explored according to quartiles of change in steps per day. Results Patients in the highest quartiles of steps per day change lost more FM (3rd = −19.5 kg and 4th = −22.7 kg, P < 0.05) and abdominal adipose tissue (4th = −313 cm 2 , P < 0.05), maintained skeletal muscle mass (3rd = −3.1 cm 2 and 4th = −4.5 cm 2 , P < 0.05), and had greater reductions in resting metabolic rate. Decreases in sedentary EE and increases in light EE and age were significant predictors of both Δweight and ΔFM (R 2 = 73.8% and R 2 = 70.6%, respectively). Conclusions Nondiabetic patients who perform higher, yet still modest, amounts of PA following RYGB have greater energy deficits and lose more weight and FM, while maintaining higher skeletal muscle mass.