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Weight change in the first 2 months of a lifestyle intervention predicts weight changes 8 years later
Author(s) -
Unick Jessica L.,
Neiberg Rebecca H.,
Hogan Patricia E.,
Cheskin Lawrence J.,
Dutton Gareth R.,
Jeffery Robert,
Nelson Julie A.,
PiSunyer Xavier,
West Delia Smith,
Wing Rena R.
Publication year - 2015
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1002/oby.21112
Subject(s) - medicine , odds , odds ratio , obesity , weight change , weight loss , demography , logistic regression , sociology
Objective Examine the relationship between 1‐ and 2‐month weight loss (WL) and 8‐year WL among participants enrolled in a lifestyle intervention. Methods 2,290 Look AHEAD participants (BMI: 35.65 ± 5.93 kg/m 2 ) with type 2 diabetes received an intensive behavioral WL intervention. Results 1‐ and 2‐month WL were associated with yearly WL through Year 8 ( P 's < 0.0001). At Month 1, participants losing 2‐4% and >4% had 1.62 (95% CI: 1.32, 1.98) and 2.79 (95% CI: 2.21, 3.52) times higher odds of achieving ≥5% WL at Year 4 and 1.28 (95% CI: 1.05,1.58) and 1.77 (95% CI: 1.40, 2.24) times higher odds of achieving ≥5% WL at Year 8, compared to those losing <2% initially. At Month 2, 3‐6% WL resulted in greater odds of achieving ≥5% WL at Year 4 (OR = 1.85; CI: 1.48, 2.32), and >6% WL resulted in the greatest odds of achieving ≥5% WL at Year 4 (OR = 3.85; CI: 3.05, 4.88) and Year 8 (OR = 2.28; CI: 1.81, 2.89), compared to those losing <3%. Differences in adherence between WL categories were observed as early as Month 2. Conclusions 1‐ and 2‐month WL was associated with 8‐year WL. Future studies should examine whether alternative treatment strategies can be employed to improve treatment outcomes among those with low initial WL.