Premium
Neural bases of food perception: Coordinate‐based meta‐analyses of neuroimaging studies in multiple modalities
Author(s) -
Huerta Claudia I.,
Sarkar Pooja R.,
Duong Timothy Q.,
Laird Angela R.,
Fox Peter T.
Publication year - 2014
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1002/oby.20659
Subject(s) - neuroimaging , functional neuroimaging , neural substrate , functional magnetic resonance imaging , stimulus (psychology) , neuroscience , insula , psychology , modalities , brain mapping , perception , brain activity and meditation , transcranial magnetic stimulation , medicine , cognitive psychology , stimulation , cognition , electroencephalography , social science , sociology
Objective The purpose of this study was to compare the results of the three food‐cue paradigms most commonly used for functional neuroimaging studies to determine: i) commonalities and differences in the neural response patterns by paradigm and ii) the relative robustness and reliability of responses to each paradigm. Methods Functional magnetic resonance imaging studies using standardized stereotactic coordinates to report brain responses to food cues were identified using online databases. Studies were grouped by food‐cue modality as: i) tastes (8 studies); ii) odors (8 studies); and, iii) images (11 studies). Activation likelihood estimation was used to identify statistically reliable regional responses within each stimulation paradigm. Results Brain response distributions were distinctly different for the three stimulation modalities, corresponding to known differences in location of the respective primary and associative cortices. Visual stimulation induced the most robust and extensive responses. The left anterior insula was the only brain region reliably responding to all three stimulus categories. Conclusions These findings suggest visual food‐cue paradigm as promising candidate for imaging studies addressing the neural substrate of therapeutic interventions.