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Hyperphagia: Current concepts and future directions proceedings of the 2nd international conference on hyperphagia
Author(s) -
Heymsfield Steven B.,
Aveicole M.,
Baier Leslie,
Brantley Phillip,
Bray George A.,
Burnett Lisa C.,
Butler Merlin G.,
Driscoll Daniel J.,
Egli Dieter,
Elmquist Joel,
Forster Janice L.,
Goldstone Anthony P.,
Gourash Linda M.,
Greenway Frank L.,
Han Joan C.,
Kane James G.,
Leibel Rudolph L.,
Loos Ruth J.F.,
Scheimann Ann O.,
Roth Christian L.,
Seeley Randy J.,
Sheffield Val,
Tauber Maïthé,
Vaisse Christian,
Wang Liheng,
Waterland Robert A.,
Wevrick Rachel,
Yanovski Jack A.,
Zinn Andrew R.
Publication year - 2014
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1002/oby.20646
Subject(s) - scope (computer science) , population , medicine , political science , computer science , environmental health , programming language
Objective Hyperphagia is a central feature of inherited disorders (e.g., Prader–Willi Syndrome) in which obesity is a primary phenotypic component. Hyperphagia may also contribute to obesity as observed in the general population, thus raising the potential importance of common underlying mechanisms and treatments. Substantial gaps in understanding the molecular basis of inherited hyperphagia syndromes are present as are a lack of mechanistic of mechanistic targets that can serve as a basis for pharmacologic and behavioral treatments. Design and Methods International conference with 28 experts, including scientists and caregivers, providing presentations, panel discussions, and debates. Results The reviewed collective research and clinical experience provides a critical body of new and novel information on hyperphagia at levels ranging from molecular to population. Gaps in understanding and tools needed for additional research were identified. Conclusions This report documents the full scope of important topics reviewed at a comprehensive international meeting devoted to the topic of hyperphagia and identifies key areas for future funding and research.