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Validation of the measurement of intra‐abdominal fat between ultrasound and CT scan in women with obesity and infertility
Author(s) -
Kuchenbecker Walter K. H.,
Groen Henk,
Pel Heleen,
Bolster Johanna H. T.,
Wolffenbuttel Bruce H. R.,
Land Jolande A.,
Hoek Annemieke,
Corpeleijn Eva
Publication year - 2014
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1002/oby.20452
Subject(s) - medicine , infertility , limits of agreement , ultrasound , prospective cohort study , obesity , abdominal fat , computed tomography , nuclear medicine , radiology , surgery , pregnancy , genetics , biology
Objective To compare the means and changes over time of intra‐abdominal fat (IAF) and subcutaneous abdominal fat (SAF) measured by abdominal ultrasound (US) and computerized tomography (CT). Design and Methods Prospective cohort study of 53 women with obesity and infertility undergoing a lifestyle program. Results The Pearson's correlation between IAF measurement by US compared to CT was good at baseline, month 3 and 6 (all r ≥ 0.72). The correlation of SAF measurement by US compared to CT was reasonable at baseline ( r = 0.54; 95%CI 0.30‐0.78) and weak at month 3 and 6 (all r ≤ 0.39). The correlation between the changes in IAF over 3 and 6 months by US compared to CT was reasonable and significant respectively (all r > 0.48). US could not measure the changes of SAF over time. The Bland–Altman plot showed good agreement between US and CT for IAF measurements (−1.1 [95%CI ‐3.9‐1.6] cm lower mean in US) at baseline. For changes of IAF over time, mean estimates were in agreement. Conclusion In women with obesity and infertility, measuring IAF by US is in good agreement with the CT scan methodology but the measurement of SAF by US is unreliable.