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Obesity and colorectal adenomatous polyps: A cross‐sectional study in Korean adults
Author(s) -
Lee Ji Young,
Kwak Sang Mi,
Myung SeungKwon,
Jee Sun Ha
Publication year - 2014
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1002/oby.20390
Subject(s) - medicine , obesity , colorectal cancer , colonoscopy , odds ratio , adenomatous polyps , cross sectional study , abdominal obesity , logistic regression , gastroenterology , body mass index , cancer , metabolic syndrome , pathology
Objective This study aimed to examine the association between obesity and the risk of colorectal adenomatous polyps. Design and Methods The design of this study is a cross‐sectional study. A total of 1,574 participants (818 males and 756 females), who had undergone colonoscopy for health examinations at the National Cancer Center hospital in South Korea from February to September 2009, were included in the analysis. Results The prevalence of colorectal adenomatous polyps was 39.5% in males and 22.6% in females. In multiple logistic regression analysis, obesity (odds ratio [OR] = 1.69, 95% CI = 1.16‐2.48) and abdominal obesity (OR = 1.59, 95% CI = 1.13‐2.23) were significantly associated with an increased risk of colorectal adenomatous polyps in males, but not in females. In the subgroup analyses by age, obesity (OR = 2.27, 95% CI = 1.32‐3.89), and abdominal obesity (OR = 1.76, 95% CI = 1.12‐2.76) significantly increased a risk of colorectal adenomatous polyps in males aged <50 years, but not in males aged ≥50 years. However, interaction terms were not significant between obesity and gender ( P = 0.397) and between obesity and age ( P = 0.531) in the overall analyses. Conclusion Our findings should be explored in further research.