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Early changes of abdominal adiposity detected with weekly dual bioelectrical impedance analysis during calorie restriction
Author(s) -
Ida Midori,
Hirata Masakazu,
Odori Shinji,
Mori Eisaku,
Kondo Eri,
Fujikura Junji,
Kusakabe Toru,
Ebihara Ken,
Hosoda Kiminori,
Nakao Kazuwa
Publication year - 2013
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1002/oby.20300
Subject(s) - bioelectrical impedance analysis , medicine , calorie , calorie restriction , dual energy x ray absorptiometry , dual energy , obesity , diabetes mellitus , abdominal obesity , weight loss , waist , body mass index , endocrinology , osteoporosis , bone mineral
Objective To elucidate early change of intra‐abdominal fat in response to calorie restriction in patients with obesity by weekly evaluation using a dual bioelectrical impedance analysis (Dual BIA) instrument. Methods For 67 Japanese patients with obesity, diabetes, or metabolic syndrome, intra‐abdominal fat area (IAFA), initially with both Dual BIA and computed tomography (CT), and in subsequent weeks of calorie restriction, with Dual BIA were measured. Results IAFA by Dual BIA (Dual BIA‐IAFA) correlated well with IAFA by CT (CT‐IAFA) in obese patients ( r = 0.821, P < .0001, n = 67). Ten males and 9 females (age 49.0 ± 14.4 years, BMI 33.2 ± 7.3 kg/m 2 ) lost more than 5% of baseline body weight (BW) in 3 weeks, and their Dual BIA‐IAFA, BW, and WC decreased by 18.9%, 5.3%, and 3.8%, respectively ( P < .05, ANCOVA). Conclusion Dual BIA instrument could detect the weekly change of Dual BIA‐IAFA under calorie restriction in obese patients and demonstrated a substantially larger change of IAFA compared with changes of BW and WC in early weeks. This observation corroborates the significance of evaluating IAFA as a biomarker for obesity, and indicates the clinical usefulness of the Dual BIA instrument.