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Changes in myocardial mechanics in patients with obesity following major weight loss after bariatric surgery
Author(s) -
Koshino Yuki,
Villarraga Hector R.,
Somers Virend K.,
Miranda William R.,
Garza Carolina A.,
Hsiao JuFeng,
Yu Yang,
Saleh Haydar K.,
LopezJimenez Francisco
Publication year - 2013
Publication title -
obesity
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.438
H-Index - 199
eISSN - 1930-739X
pISSN - 1930-7381
DOI - 10.1002/oby.20168
Subject(s) - medicine , ejection fraction , weight loss , ventricle , cardiology , obesity , speckle tracking echocardiography , diastole , weight change , surgery , heart failure , blood pressure
Objective The purpose of this study was to evaluate myocardial mechanics in obese subjects using 2D‐speckle tracking echocardiography (2D‐STE). Design and Methods 63 obese individuals, including 28 who underwent bariatric surgery for weight loss (BMI 51 ± 9 kg/m 2 ) and 35 managed conservatively (BMI 43 ± 7 kg/m 2 ) were included. Changes in strain (S) and strain rate (SR) measured by 2D‐STE. Mean follow‐up was 23 ± 10 months. Results The surgery group had a significant weight loss (BMI 37 ± 10 kg/m 2 , P < 0.0001), but no change was noted in the nonsurgery group (BMI 42 ± 7 kg/m 2 , P = 0.1). For the surgery group, S and SR in early diastole (SRe) improved significantly in the longitudinal left ventricle (LV) (S: P = 0.0004, SRe: P = 0.02) and right ventricle (RV) (S: P = 0.02, SRe: P = 0.009), whereas no changes were seen in LV ejection fraction (LVEF). In the nonsurgery group, there was no change in S, SR, or body weight. For all patients, weight changes correlated significantly with changes in LV S ( r = 0.43, P = 0.0005). Conclusions The improvement of S after bariatric surgery suggests that weight loss could improve myocardial performance, despite the lack of change in LVEF.