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Multiple Cases with Probable Treponemal Infection from 16th to 19th Centuries Romania
Author(s) -
Radu C.,
Andreica L.,
Constantinescu M.,
Soficaru A.
Publication year - 2015
Publication title -
international journal of osteoarchaeology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.738
H-Index - 60
eISSN - 1099-1212
pISSN - 1047-482X
DOI - 10.1002/oa.2444
Subject(s) - leprosy , paleopathology , treponematosis , pathological , tuberculosis , differential diagnosis , medicine , osteomyelitis , pathology , dermatology , syphilis , human immunodeficiency virus (hiv) , surgery , sexually transmitted disease , family medicine
In this paper, we describe pathological lesions identified in seven skeletons discovered in the Saint Sava necropolis in Bucharest, Romania, dating to the Late Medieval/Early Modern period. The pathological changes observed in the skeletons were analysed using macroscopic examination. Additionally, computed tomography scanning was performed on two individuals displaying advanced lesions on the cranial surface. For the differential diagnosis, we took into consideration treponemal infection, tuberculosis, osteomyelitis, leprosy, fluorosis, melorheostosis, hypertrophic pulmonary osteoarthropathy, Paget's disease and mycotic infection, along with the possibility of multiple afflictions occurring simultaneously. The morphology and distribution of the lesions are suggestive of treponematosis, which, to our knowledge, makes this the first case of this disease on the Romanian territory in archaeological populations. Copyright © 2015 John Wiley & Sons, Ltd.