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Ovarian steroids and premenstrual symptoms: A comparison of group differences and intra‐individual patterns
Author(s) -
Lentz Martha J.,
Woods Nancy,
Heitkemper Margaret,
Mitchell Ellen,
Henker Richard,
Shaver Joan
Publication year - 2007
Publication title -
research in nursing and health
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.836
H-Index - 85
eISSN - 1098-240X
pISSN - 0160-6891
DOI - 10.1002/nur.20188
Subject(s) - pregnanediol , menstrual cycle , medicine , hormone , endocrinology , physiology , urine , luteal phase , menstruation , gynecology , psychology
To examine the relationship of gonadal hormone and symptom patterns across the menstrual cycle, women screened for 2–3 cycles completed an intensive study cycle; 26 had a low‐severity symptoms (LS), 20, a premenstrual syndrome (PMS), and 26, a premenstrual magnification pattern (PMM). All completed daily symptom diaries and collected late afternoon urine samples which were assayed for pregnanediol and estradiol for that cycle. The PMS and PMM groups had significantly more positive cross‐correlations of pregnanediol and symptoms than the LS group. Women in all groups had similar levels of estradiol and pregnanediol. Women with PMS and PMM patterns responded to progesterone differently than women with LS patterns: thus the former groups may not benefit from hormone therapies. © 2007 Wiley Periodicals, Inc. Res Nurs Health 30: 238–249, 2007