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Finite‐volume scheme for a degenerate cross‐diffusion model motivated from ion transport
Author(s) -
Cancès Clément,
ChainaisHillairet Claire,
Gerstenmayer Anita,
Jüngel Ansgar
Publication year - 2019
Publication title -
numerical methods for partial differential equations
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.901
H-Index - 61
eISSN - 1098-2426
pISSN - 0749-159X
DOI - 10.1002/num.22313
Subject(s) - finite volume method , mathematics , degenerate energy levels , degeneracy (biology) , mathematical analysis , statistical physics , physics , mechanics , quantum mechanics , bioinformatics , biology
An implicit Euler finite‐volume scheme for a degenerate cross‐diffusion system describing the ion transport through biological membranes is proposed. The strongly coupled equations for the ion concentrations include drift terms involving the electric potential, which is coupled to the concentrations through the Poisson equation. The cross‐diffusion system possesses a formal gradient‐flow structure revealing nonstandard degeneracies, which lead to considerable mathematical difficulties. The finite‐volume scheme is based on two‐point flux approximations with “double” upwind mobilities. The existence of solutions to the fully discrete scheme is proved. When the particles are not distinguishable and the dynamics is driven by cross diffusion only, it is shown that the scheme preserves the structure of the equations like nonnegativity, upper bounds, and entropy dissipation. The degeneracy is overcome by proving a new discrete Aubin–Lions lemma of “degenerate” type. Numerical simulations of a calcium‐selective ion channel in two space dimensions show that the scheme is efficient even in the general case of ion transport.

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